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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF22
All Species:
20.91
Human Site:
S412
Identified Species:
46
UniProt:
Q14807
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14807
NP_015556.1
665
73262
S412
P
E
E
E
E
I
G
S
P
E
P
M
A
A
P
Chimpanzee
Pan troglodytes
XP_510910
679
74714
S412
P
E
E
E
E
I
G
S
P
E
P
M
A
A
P
Rhesus Macaque
Macaca mulatta
XP_001104365
657
72278
S401
P
E
E
E
E
I
G
S
A
E
P
M
A
A
S
Dog
Lupus familis
XP_547058
651
71817
S395
P
E
E
E
E
I
G
S
P
E
P
P
A
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3V300
660
73171
S407
P
E
E
E
S
T
G
S
P
E
S
T
A
A
P
Rat
Rattus norvegicus
Q5I0E8
657
73037
S404
P
E
E
E
S
T
G
S
P
E
S
T
A
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZYL5
650
73149
D399
Q
R
K
K
S
K
T
D
S
T
E
S
S
P
N
Zebra Danio
Brachydanio rerio
A8WFU8
634
70574
S383
G
E
P
Q
N
K
R
S
K
E
G
K
K
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46867
784
88189
K396
K
Q
R
V
K
K
P
K
K
E
T
V
T
K
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46873
699
78760
R457
N
T
Q
L
K
Q
K
R
M
K
Q
L
K
E
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPC6
894
98404
E456
Q
A
Q
N
R
I
S
E
V
E
K
N
F
A
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
94.8
90
N.A.
81.3
81
N.A.
N.A.
N.A.
52.3
50.9
N.A.
29.2
N.A.
28.1
N.A.
Protein Similarity:
100
97.5
96.2
93
N.A.
88.7
88.8
N.A.
N.A.
N.A.
69.3
66.1
N.A.
46.1
N.A.
45.7
N.A.
P-Site Identity:
100
100
86.6
93.3
N.A.
73.3
73.3
N.A.
N.A.
N.A.
0
26.6
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
100
86.6
93.3
N.A.
73.3
73.3
N.A.
N.A.
N.A.
20
33.3
N.A.
26.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
10
0
0
0
55
73
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
64
55
55
37
0
0
10
0
82
10
0
0
10
28
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
10
0
0
0
0
0
55
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
46
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
10
10
19
28
10
10
19
10
10
10
19
10
0
% K
% Leu:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
28
0
0
0
% M
% Asn:
10
0
0
10
10
0
0
0
0
0
0
10
0
0
10
% N
% Pro:
55
0
10
0
0
0
10
0
46
0
37
10
0
10
46
% P
% Gln:
19
10
19
10
0
10
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
10
10
0
10
0
10
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
28
0
10
64
10
0
19
10
10
0
10
% S
% Thr:
0
10
0
0
0
19
10
0
0
10
10
19
10
0
0
% T
% Val:
0
0
0
10
0
0
0
0
10
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _